Anthony, R.M.

Anthony, R.M.

Research coordinator Tuberculosis
KIT Biomedical Research
Mycobacterial research / Tuberculose
Phone: +31 (0)205665450
E-mail: r.anthony@kit.nl


Richard M Anthony, PhD research coordinator for the tuberculosis research group in KIT-Biomedical Research, is a Molecular Biologist who joined the KIT in 2001. Specialized in molecular diagnostics, he has extensive experience in development of molecular tests for bacterial drug resistance, bacterial and fungal typing, and microarray based diagnostics.
Between April 1996 and May 2001 he was employed by King's College London, UK, on the epidemiology and rapid detection of bacterial infection with a focus on the laboratory diagnosis of hospital acquired infection particularly MRSA.Currently, his work is directed towards improving tuberculosis diagnostics, understanding the acquisition of drug resistance in Mycobacterium tuberculosis and adapting and simplifying multiplex assays methods so they can be more widely applied for diagnostic use. This ranges from work on improving the provision of smear microscopy to the development of multiplex molecular assays to study drug resistance in M. tuberculosis.The work of the KIT-TB group was instrumental in the recent development and provision of LED fluorescent microscopy for TB diagnostics. Our work also explores the mechanism of drug resistance acquisition in tuberculosis and the detection of drug resistance in multiple international research projects and collaborations with industry.

Selected publications

  1. den Hertog AL, Visser DW, Ingham CL, Fey FHAG, Klatser PR, Anthony RM. Simplified Automated Image Analysis for Detection and Phenotyping of Mycobacterium tuberculosis on Porous Supports by Monitoring Growing Microcolonies. PLoS ONE 2010 5:e11008. doi:10.1371/journal.pone.0011008.
  2. Bergval IL,  Schuitema ILJ,  Klatser PR, Anthony RM. Resistant Mutants of Mycobacterium tuberculosis  selected in vitro do not reflect the in vivo mechanism of isoniazid resistance. Journal of Antimicrobial Chemotherapy 2009 64:515-523.
  3. Anthony RM, Cobelens FJG, Gebhard A, Klatser PR, Lumb R, Rüsch-Gerdes S, van Soolingen D. Liquid culture for Mycobacterium tuberculosis: proceed but with caution. International Journal of Tuberculosis and Lung Diseases 2009 13:1051-1053.
  4. Bergval IL,Vijzelaar RNCP, Dalla Costa ER, Schuitema ARJ, Oskam L, Kritski AL, Klatser PR, Anthony RM. Development of a multiplex assay for the rapid characterisation of Mycobacterium tuberculosis. J. Clin. Microbiol. Feb, 2008; doi:10.1128/JCM.01821-07.
  5. Nguyen Van Hung, Dinh Ngoc Sy, Richard M Anthony, Frank GJ Cobelens and Dick van Soolingen. Fluorescence microscopy for tuberculosis diagnosis. Lancet Infectious Diseases 2007; 7:238-239.
  6. Anthony RM, Kolk A.H.J., Kuijper S., Klatser P.R. Light emitting diodes for auramine O fluorescence microscopic screening of Mycobacterium tuberculosis. International Journal of Tuberculosis and Lung Disease 2006; 10:1060-1062.
 

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Address

KIT Biomedical Research
Meibergdreef 39
1105 AZ Amsterdam
The Netherlands

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