The Centre for Applied Spatial Epidemiology (CASE) supports health professionals to make data-informed decisions.
CASE provides unique geographic analysis of health data and new opportunities for health professionals to understand and learn from local variations in disease. That means that Governments and NGOs can prioritise health care interventions where they are needed the most.
Small data for big decisions
KIT Royal Tropical Institute established CASE to improve health interventions by aligning epidemiological approaches with evidence-based best practices. We work together with governments, institutes and NGOs in low-to-middle-income countries, while encouraging health managers to use available data and spatial analysis techniques to improve decision making and more effectively deliver health care to all.
CASE combines technical expertise in the fields of spatial statistics, geo-data management and impact evaluations with a broad content knowledge of various infectious and neglected tropical diseases—including Tuberculosis (TB), HIV, and Malaria, among others—to support disease control programs.
Over the last decade, we have been a leader in spatial epidemiology research as well as the development of Geographic Information System (GIS) tools and services for disease control.
Visualising the local nature of disease
Epidemiology traditionally focuses on the local conditions of a fixed geographical area where people experience disease. However, innovations in GIS and geoinformation technologies now allow us to measure and quantify the increasingly mobile and dynamic environment in which people are exposed to health risks and disease.
At CASE, we provide the tools to visualise the local nature, progression and spread of disease.
Understanding why tuberculosis cases are missed in Bangladesh
In August 2017, a data analysis workshop was organised in Dhaka, Bangladesh, during which stakeholders from various Bangladeshi institutions – including BRAC, MSH and ICDDR Bangladesh – worked together to generate new hypotheses about where missing cases of TB are found, whom they may be, why they may be missed, and which solutions are needed to reach and care for them. Building on the extensive knowledge of the KIT CASE team, maps were produced and presented to assess these questions. This followed KIT’s Bangkok workshop on its MATCH Approach to tuberculosis care in 2017.Read more about Understanding why tuberculosis cases are missed in Bangladesh
Good Epidemiological Practice
Epidemiology is the cornerstone of public health. It shapes policy decisions and evidence-based practice by identifying risk factors for disease, and targets for preventive healthcare. As the foundation of quantitative monitoring and evaluation (M&E) activities and counterfactual impact evaluations (CIE), it provides the evidence base for the scale-up of health interventions.Read more about Good Epidemiological Practice
Addressing drug-resistant Tuberculosis in Kazakhstan
The MATCH Approach
A cornerstone of the Centre for Applied Spatial Epidemiology is the MATCH Approach. This innovative geo-spatial analysis framework evaluates the effectiveness of interventions in the context of the local disease risk, burden and health efforts. This information is especially valuable in informing local interventions.
We link data to policy objectives, combine and simplify complex data into a more intuitive format and build capacity for data management and analysis. The MATCH Approach employs and analyses multiple — and often underused — sources of geographically, temporally and demographically disaggregated data on epidemiological risk factors. This enables decision makers to use their program data to make better informed decisions supported by local evidence.
MATCH is currently being applied to support TB programs around the world to identify persistent gaps in program functioning which lead to over four million people with TB not being diagnosed or reported globally. MATCH consequently provides a valuable tool to identify geographic areas where TB case detection, diagnosis and reporting can be strengthened.
Training & Education
Using innovative geo-spatial tools opens new perspectives on how we consider the effect of geographic contexts on health, and especially disease. To ensure that these innovations are accessible and become embedded in routine analyses and presentation, continuous knowledge transfer and capacity building amongst data managers, analysts and M&E experts is required.
Simultaneously, outputs of the application of analytical tools need to be critically appraised and interpreted within local context to provide value for planning. As part of our projects and program support, we also train local counterparts and work closely with stakeholders. As a result, we build capacity and create ownership of the process and outcomes which will inform health planning, beyond the support provided by KIT.
KIT also houses an education centre with Masters’ programmes and advanced courses for health professionals — all aimed at strengthening health systems around the world. The courses are offered in cooperation with the Vrije Universiteit Amsterdam.
Data disclosure & processing
Much of the effort required to generate maps and apply spatial analysis to routinely collected programme data relies on the availability and accessibility of health data. Recently, many health programmes have adopted electronic data systems, such as the DHIS2, to collect, store an manage project data. This data is generally accessible via customizable interfaces which allow users to perform basic analysis for monitoring purposes.
To leverage these applications and fully disclose the data contained within these resources, CASE developed a GIS plugin which makes data stored and managed using DHIS2 fully interoperable with Quantum GIS, therefore enabling the integration of data across various geographic units and scales.
Comparison of two Gram stain point-of-care systems for urogenital gonorrhoea among high-risk patients
Diagnostic accuracy and cost-effectiveness before and after changing the screening algorithm at an STI clinic in Amsterdam.