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Comparative Meta-Analysis of Tuberculosis Contact Investigation Interventions in Eleven High Burden Countries.

L. Blok, S. Sahu, J. Creswell, R. Stevens, M.I. Bakker

Screening of household contacts of tuberculosis (TB) patients is a recommended strategy to improve early case detection. While it has been widely implemented in low prevalence countries, the most optimal protocols for contact investigation in high prevalence, low resource settings is yet to be determined. This study evaluated contact investigation interventions in eleven lower and middle income countries and reviewed the association between context or program-related factors and the yield of cases among contacts