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Predicting communities with hightuberculosis case-finding efficiency tooptimise resource allocation in Pakistan: comparing the performance of anegative binomial spatial lag modelwith a Bayesian machine-learningmodel

Authors
Christina Mergenthaler, Jake D. Mathewson, Stephanie Lako, Andreas Werle van der Merwe, Matthys Potgieter, Vincent Meurrens, Abdullah Latif, Hasan Tahir, Tanveer Ahmed, Zia Samad, Frank Cobelens, Daniella Brals, Mirjam I Bakker, Ente Rood
Publication year
February 2025

Despite progress in tuberculosis (TB) treatment coverage in past years, an estimated 183000 people with TB may not have been diagnosed in Pakistan in 2022. Therefore, there is a need to develop models which help to steer active case finding (ACF) towards populations with a high probability of having undetected TB. The aim of this study was to cross-validate TB positivity rate predictions in ACF settings of an existing Bayesian machine learning (BML) with a simpler frequentist model.