An Approach to Understanding the Transmissionof Mycobacterium leprae Using Molecular and Immunological Methods: Results from the MILEP2 Study


W.C.S. Smith, C.M. Smith, I.A. Cree, R.S. Jadhav, M. Macdonald, V.K. Edward, L. Oskam, S.M. van Beers, P.R. Klatser

Important developments have taken place over the past decade in tackling the global leprosy burden. There has been a very significant reduction of over 90% in the total number of leprosy patients registered for treatment through the implementation of multidrug therapy regimes that have dramatically reduced the duration of treatment. However, despite this reduction in registered prevalence of leprosy, there has been no parallel reduction in the global case detection. This is a serious barrier to aspirations to eradicate leprosy in the future.