The INFIR Cohort Study: investigating prediction, detection and pathogenesis of neuropathy and reactions in leprosy


W.H. van Brakel, R.D. Nicholls, P.K. Das, P. Barkataki, S.J. Suneetha, R.S. Jadhav, P. Maddali, D. Lockwood, E. Wilder-Smith, K. V. Desikan

Leprosy is feared because of the deformities and disability that it may cause. Successful leprosy treatment should prevent or heal deformities and disabilities. Most of these are secondary complications of impaired of nerve function, often caused by immunological reactions against M. leprae antigens. Unfortunately, people remain at risk of neuropathy resulting from such reactions during and even after successful anti-leprosy treatment